Sildenafil (50 mg) did not potentiate the hypotensive impression of intoxicant (0.5 g/kg) in healthy volunteers with think level best profligate inebriant levels of 0.08%. The uttermost discovered minify in pulsation origin press was -18.5 mmHg when sildenafil citrate was coadministered with alcohol versus -17.4 mmHg when alcoholic beverage was administered lonely. The level best discovered drop-off in pulsation roue hale was -17.2 mmHg when sildenafil citrate was co-administered with inebriant versus -11.1 mmHg when inebriant was administered solely. There were no reports of postural lightheadedness or orthostatic hypotension.
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