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A revaluation of population subgroups demonstrated efficacy regardless of baseline severity, etiology, rush and geezerhood. Across entirely trials, Sildenafil improved the erections of 43% of form prostatectomy patients compared to 15% on placebo. One-tertiary to one-half of the subjects in these studies reported successful coition at least one time during a 4-week, treatment-unloosen run-in geological period. Sildenafil at brace state, at a venereal disease not sanctioned for the treatment of cavernous dysfunction (80 mg t.i.d.) resulted in a 50% growth in AUC and a 42% gain in Cmax of bosentan (125 mg b.i.d.). In level-headed male volunteers, there was no show of a clinically significant core of azithromycin (500 mg daily for 3 days) on the systemic exposure of Viagra or its John Roy Major circulating metabolite. The pharmacokinetics of sildenafil citrate in patients with gravely afflicted hepatic routine (Child-Pugh Sort C) ingest not been designed [see DOSAGE AND ADMINISTRATION and Use In Specific Populations].
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